Ronald Acuña Jr. wasn't going to let Wednesday's game end without making even more MLB history.

His steal of second base in the 10th inning of a hard-fought matchup between the Atlanta Braves and Chicago Cubs was Acuña's second of the night and 70th this season, making him the first player in MLB history to hit at least 40 home runs and steal 70 bases.

The end has officially arrived for this year's New York Yankees.

While a bevy of key injuries and a season's worth of offensive struggles long made it seem that their run of six straight postseason appearances was likely going to be halted, that conclusion mercifully and officially arrived on a Sunday afternoon at Yankee Stadium.

Under a steady, relentless rainfall and amid powerful, gusty winds brought on by nearby Tropical Storm Ophelia, the Yankees lost to the Arizona Diamondbacks 7-1, falling out of contention for the final wild-card spot.

 Mookie Betts hit a two-run double in the eighth inning on Saturday night, giving the Los Angeles Dodgers outfielder 105 RBIs, the most ever by a leadoff hitter.

During a 7-0 victory over the rival San Francisco Giants, Betts doubled to center off San Francisco's Ross Stripling, scoring Austin Barnes and David Peralta and extending the Dodgers' lead to seven runs. Betts doubled in the seventh too and walked twice for the National League West champions.

The Houston Astros fell two outs shy of a combined no-hitter against the Oakland Athletics on Wednesday night.

Hunter Brown and the Astros held the A's hitless until Ryan Noda's one-out single in the ninth inning of the 6-2 victory, which sent Oakland to its first consecutive 100-loss seasons since the 1960s.

Brown pitched five innings, and Rafael Montero, Hector Neris and Bryan Abreu followed with perfect innings each as Houston retired 11 straight batters.

Seth Brown's single and Shea Langeliers' sacrifice fly drove in runs before Pressly finished the two-hitter by throwing a called third strike past Brent Rooker.

Dusty Baker said they didn't talk about the no-hitter in the dugout, but that everyone was certainly thinking about it.

"I'm sure all the relievers were aware of it, conscious of it because they had been part of two other combined no-hitters," he said. "So they knew, and Pressly was upset because he wanted to be part of it again. But it was spoiled."

Matt Olson was raised an Atlanta Braves fan and appreciated the significance of the stars he passed on the way up the franchise's single-season home run list. Hall of Famers Hank Aaron and Eddie Mathews were among those sluggers left behind as Olson crushed one homer after another in a career campaign for the best team in baseball.

With home run Nos. 49 and 50 on Monday against the Phillies -- the first one launched off the second deck and the second sliced the opposite way to left field -- Olson entered rarified air among Atlanta's greats.

The Atlanta Braves became the first team to clinch a playoff berth, rallying to beat the Pittsburgh Pirates 5-2 on Sunday as Matt Olson went 2-for-3 with three RBIs.

Atlanta (93-49) reached the postseason for the sixth straight year, the second-longest streak in franchise history. The Braves won 11 straight NL East titles from 1995 to 2005.

Seattle Mariners right-hander George Kirby regrets one pitch from Friday night and didn't even want to be on the mound when it happened.

Kirby gave up a game-tying two-run homer to Tampa Bay's René Pinto in the seventh inning on what was his 102nd and final pitch of the game.

"I wish I wasn't out there for the seventh [inning], to be honest," Kirby said after the game.

"I was at 90 pitches," Kirby explained, "and I didn't think I really could go any more. But it is what it is."

Jose Altuve homered in each of the first three innings Tuesday night, leading the Houston Astros' explosive beginning in their rivalry clash with the Texas Rangers.

The barrage gave Altuve homers in four straight plate appearances going back to Monday's game and five homers in six plate appearances -- the most in a two-game span in Astros history and tied for the most over two games in MLB history.

Giancarlo Stanton reached a career milestone Tuesday night, hitting his 400th home run as the New York Yankees defeated the Detroit Tigers 5-1.

Stanton's two-run homer off reliever Jose Cisnero broke a 1-all tie in the sixth inning. The slugger reached 400 homers in 1,520 career games -- fourth fastest in major league history, behind Mark McGwire (1,412), Babe Ruth (1,475) and Alex Rodriguez (1,489). Albert Pujols is fifth at 1,523.

All-Star slugger Pete Alonso homered twice and drove in four runs, reaching 40 homers and 100 RBIs for the second consecutive season as the New York Mets beat the first-place Seattle Mariners 6-3 on Sunday.

Alonso hit an RBI single in the first inning before his two-run shot in the third made him the fifth player in major league history with at least three 40-homer seasons in his first five campaigns, joining Hall of Famers Ralph Kiner (four times), Eddie Mathews, Ryan Howard and Albert Pujols.